The paper will present extensive grids of non-LTE departure coefficients for ~13 different elements, the first paper of its kind. These grids were used for GALAH DR3. The results of the paper will however be based on a separate, line-by-line re-analysis of a subset of GALAH DR3 (~50000 stars), in LTE and in non-LTE. This will demonstrate the importance of taking departures from LTE into account in spectroscopic studies, when it comes to studying the mean Galactic chemical evolution and its dispersion.